MDT is a biotherapy that uses live, sterile maggots (fly larvae) to clean non-healing wounds.

Medical maggots help speed healing by:

1. Removing dead and infected tissue, and

2. Disinfecting the wound by killing off bacteria.

MEDIFLY debrides chronic wounds more effectively and efficiently than traditional surgical debridement and is a great alternative for patients who are poor candidates for surgery & anesthesia.

MEDIFLY is ISO13485-certified and Cuprina Wound Solutions is the first Maggot Debridement Therapy (MDT) manufacturer in the world with this certification in addition to the Health Science Authority (HSA) Class Medical Device certification. MEDIFLY is manufactured with medical grade sterile maggots that are bacteria and virus free.​

MEDIFLY is a Bio-dressing made up of Live medical grade Lucilla cuprina (Bronze bottlefly) larvae or ‘maggots’ used to debride, clean and disinfect chronic wounds. The process by which live maggots are placed in a necrotic wound is known as Maggot Debridement Therapy (MDT).​ The maggots secrete strong proteolytic enzymes which selectively liquefy devitalized tissue including MRSA but without damaging healthy tissue. In addition, they digest the necrotic tissue and bacteria while secreting strong antimicrobials to help combat infection. ​

Compared to other forms of debridement (surgical / sharp, mechanical, enzymatic or autolytic), MDT has been shown to have the following advantages:

1. Accuracy - maggots target necrotic tissue without damaging adjacent healthy tissue in the process.

2. Inflammation - studies have shown that lucifensin, a defensin peptide from the maggot’s excretions, contains antibacterial properties capable of disinfecting wounds and helping reduce chronic inflammation.

3. Drug-resistance - for the treatment of wounds infected by MRSA, the excretions from maggots exhibited a strong and rapid disinfection action.

1. Reduces treatment time to achieve a positive clinical outcome

2. Increases the success rate of limb salvaging / retention

3. Can be conducted bedside or in the home setting (no surgery required)

4. Low level of pain / discomfort compared to surgical procedures

5. More affordable than surgical procedures